Coenzyme Q10 is found in high concentrations in the mitochondria (power house) of every cell, it is involved in the energy metabolism (electron transport) of cells. As an energy (electron) carrier, the CoQ10 molecule is continually going through an oxidation-reduction cycle. As it accepts electrons, it becomes reduced (Ubiquinol) and becomes oxidized again (Ubiquinone) as it gives up electrons. As such it is a powerful antioxidant that prevents oxidative stress caused by our body’s energy metabolism. Because nearly all cellular functions depend on an adequate energy supply, CoQ10 deficiency is felt by all cells and particularly by those with high energy consumption, such as cardiac muscle cells, nerve cells and cells of the immune system.
CoQ10 can be synthesised by the body and therefore there is no need for CoQ10 in diets of healthy individuals. There are, however, a number of reported health benefits that can be achieved in populations with either hypertension, heart failure, dementia or people that take statins. Below the specific cardiovascular disease related health benefits of CoQ10 will be summarized.
Hypertension
Endothelial dysfunction
.