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High Blood Sugar Levels Treatment

Coenzyme Q10 is found in high concentrations in the mitochondria (power house) of every cell, it is involved in the energy metabolism (electron transport) of cells. As an energy (electron) carrier, the CoQ10 molecule is continually going through an oxidation-reduction cycle. As it accepts electrons, it becomes reduced (Ubiquinol) and becomes oxidized again (Ubiquinone) as it gives up electrons. As such it is a powerful antioxidant that prevents oxidative stress caused by our body’s energy metabolism. Because nearly all cellular functions depend on an adequate energy supply, CoQ10 deficiency is felt by all cells and particularly by those with high energy consumption, such as cardiac muscle cells, nerve cells and cells of the immune system.

CoQ10 can be synthesised by the body and therefore there is no need for CoQ10 in diets of healthy individuals. There are, however, a number of reported health benefits that can be achieved in populations with either hypertension, heart failure, dementia or people that take statins. Below the specific cardiovascular disease related health benefits of CoQ10 will be summarized.

Hypertension

Two meta-analyses one consisting of 3 clinical trials containing a total of 96 participants and one of 12 trials and 362 patients showed that treatment with CoQ10 in subjects with high blood pressure resulted in mean decreases in 11-17 mmHg in systolic and 7-10 mmHg in diastolic blood pressure without significant side effects ( 1, 2 ). A third meta-analysis concluded that favourable effects of CoQ10 on heart function (ejection fraction, exercise tolerance, cardiac output, and stroke volume) have been demonstrated in the literature, but that further research is needed to recommend CoQ10 as medical therapy ( 3 ).

Endothelial dysfunction

Endothelial dysfunction is one of the main causes of hypertension and has a role in atherosclerotic plaque development. In a recent meta-analysis of 5 clinical trials with 194 patients concluded that CoQ10 supplementation is associated with significant improvement in endothelial function ( 4 ).


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