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g toward low protein.)  You can’t do both without raising fat intake, and there is good agreement that dietary fat shouldn’t be more than 40% of your calories.   Exercise prodigiously.  Exercise right before eating can change your body’s insulin response to the sugar challenge.  Even a minute of high-intensity exercise can make a difference [ ].Vegan diets are associated with much lower incidence of diabetes.  In , vegans had half the incidence of diabetes, even after controlling for the fact that they had lower BMI.  Non-vegan vegetarian diets were not far behind. Almost all of us can benefit from supplements.  Zinc [ ] and tiny quantities of chromium might also help.  Resveratrol extends life span .  There is some evidence for thiamin (vit B1).  Large quantities of cinnamon or be helpful.   showed a substantial benefit from boswellia=frankincense.     The Bottom Line Loss of insulin sensitivity is so closely intertwined with all the diseases of old age that it is hardly distinguishable from “normal aging”.  It’s an issue that we all face, and there is a whole Chinese menu of measures you can take to better your odds for health, vitality and a long life. The mechanisms of metformin, berberine, jiaogulan and Gymnema are quite different, and there is reason to think that combining them offers more benefit than any treatmentseparately; but there is as yet no data on combined therapies.


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